what are the health risks of smokeless tobacco Using can cause serious problems, like cancers, mouth diseases, heart disease, stroke, and even nicotine poisoning in children. Quitting is key for you AND your family. https://buff.ly/2WiO5Ud The Hazards of Smokeless Tobacco

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Chew, Snuff and Snus Types The CDC categorizes smokeless tobacco into chewing tobacco (loose leaf, plug, twist) and snuff

Abbreviations cAMP Cyclic AMP EGFR Epidermal growth factor receptor ECM Extracellular matrix protein IL-1 interleukin 1 beta MIP-1 Macrophage inflammatory protein 1 alpha MMPs Matrix metalloproteinases nAChRs Nicotinic acetylcholine receptors NADPH oxidase nicotinamide adenine dinucleotide phosphate oxidase NNAA 1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal) NNAL 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol NNK 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone NNN N-nitrosonornicotine PDAC Pancreatic ductal adenocarcinoma PDGF Platelet-derived growth factor TGF- Transforming growth factor beta Footnotes Conflicts of interest: The authors disclose no conflicts

Gastroenterology 136 , 757760 (2009)